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PPP2R5D belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene Name: | protein phosphatase 2, regulatory subunit B', delta |
Synonyms: | PPP2R5D, B56D, Male-enhanced antigen-1, PP2A B subunit isoform B-delta |
Target Sequences: | NM_006245 NP_006236.1 Q14738 |
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