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PPP2R2C belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene Name: | protein phosphatase 2, regulatory subunit B, gamma |
Family/Subfamily: | Protein Phosphatase Regulatory Subunit , not assigned-Protein Phosphatase Non Catalytic |
Synonyms: | PPP2R2C, B55-GAMMA, IMYPNO, IMYPNO1, PP2A subunit B isoform gamma, PR52, PR55G |
Target Sequences: | AF086924 AAG39636.1 Q9Y2T4 |
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