PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

PPP2R2B belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B55 subfamily. Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12), a disease caused by degeneration of the cerebellum, sometimes involving the brainstem and spinal cord, and in resulting in poor coordination of speech and body movements. Multiple alternatively spliced variants, which encode different isoforms, have been identified for this gene. The 5' UTR of some of these variants includes a CAG trinucleotide repeat sequence (7-28 copies) that can be expanded to 66-78 copies in cases of SCA12.

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Products

Proteins (13)

Type

Over-Expression Lysate (11)

Recombinant (2)

Target

PPP2R2B (13)

Publications

No (13)

Tag

GST (2)

Myc-DDK (Flag) (11)

Species

Human (10)

Source

293T Cells (8)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (2)

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PPP2R2B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116554

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.5 kDa

Price:

100 µg/$710

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Human PPP2R2B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78359

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.5 kDa

Price:

20 µg/$150

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Human PPP2R2B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78360

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.5 kDa

Price:

20 µg/$215

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Human PPP2R2B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78361

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.5 kDa

Price:

20 µg/$150

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Human PPP2R2B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78364

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.5 kDa

Price:

20 µg/$150

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Human PPP2R2B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78362

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.5 kDa

Price:

20 µg/$150

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Human PPP2R2B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78365

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.8 kDa

Price:

20 µg/$215

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Human PPP2R2B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78367

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50.2 kDa

Price:

20 µg/$215

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Human PPP2R2B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78366

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.2 kDa

Price:

20 µg/$215

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PPP2R2B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G126952

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.5 kDa

Price:

100 µg/$494

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Human PPP2R2B Protein (Recombinant GST) (Full Length) - LS-G29856

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

74.25 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PPP2R2B Protein (Recombinant GST) (Full Length) - LS-G29857

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

78.1 kDa

Price:

10 µg/$479; 25 µg/$670

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PPP2R2B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G124618

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.5 kDa

Price:

100 µg/$494

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