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PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
PPP2R2A belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants have been described.
| Gene Name: | protein phosphatase 2, regulatory subunit B, alpha |
| Family/Subfamily: | Protein Phosphatase Regulatory Subunit , not assigned-Protein Phosphatase Non Catalytic |
| Synonyms: | PPP2R2A, B55ALPHA, B55A, PP2A subunit B isoform alpha, PR55A, PR52A |
| Target Sequences: | NM_002717 NP_002708.1 P63151 |
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