PPP1CA / PP1-Alpha

protein phosphatase 1, catalytic subunit, alpha isozyme

Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Regulates NEK2 function in terms of kinase activity and centrosome number and splitting, both in the presence and absence of radiation-induced DNA damage. Regulator of neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E.

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Products

ELISA Kits (6)

Type

Custom (3)

Sandwich (3)

Target

PPP1CA / PP1-Alpha (6)

Reactivity

Human (2)

Mouse (1)

Rat (1)

Dog (1)

Format

96-Well Strip Plate (6)

Publications

No (6)

Sample Type

Plasma (3)

Serum (3)

Tissue Homogenates (1)

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Human PPP1CA / PP1-Alpha (Sandwich ELISA) ELISA Kit - LS-F12369

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Mouse PPP1CA / PP1-Alpha (Sandwich ELISA) ELISA Kit - LS-F20480

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human PPP1CA / PP1-Alpha (Sandwich ELISA) ELISA Kit - LS-F33372

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Bovine PPP1CA / PP1-Alpha (Custom ELISA) ELISA Kit - LS-F20477

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Rat PPP1CA / PP1-Alpha (Custom ELISA) ELISA Kit - LS-F20478

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Dog PPP1CA / PP1-Alpha (Custom ELISA) ELISA Kit - LS-F20476

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Dog

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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