Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
PPOX is the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.
Gene Name: | protoporphyrinogen oxidase |
Synonyms: | PPOX, PPO, Protoporphyrinogen oxidase, V290M, Variegate porphyria, VP |
Target Sequences: | NM_000309 NP_000300.1 P50336 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.