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May negatively regulate the 4-1BB-mediated signaling cascades which result in the activation of NK-kappaB and JNK1. Probable substrate recognition subunit of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Gene Name: | leucine rich repeat protein 1 |
Synonyms: | LRR1, 4-1BBLRR, Cyclophilin-like 5, Leucine rich repeat protein 1, LRR-1, LRR-repeat protein 1, PPIL5, Leucine-rich repeat protein 1 |
Target Sequences: | NM_152329 NP_689542.2 Q96L50 |
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