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PPIL1 is a member of the cyclophilin family of peptidylprolyl isomerases (PPIases). The cyclophilins are a highly conserved, ubiquitous family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. Based on similarity to other PPIases, this protein could accelerate the folding of proteins and might catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Gene Name: | Peptidylprolyl isomerase (cyclophilin)-like 1 |
Synonyms: | PPIL1, Cyclophilin-related gene 1, HCyPX, PPIase, Rotamase PPIL1, CGI-124, CYPL1 |
Target Sequences: | NM_016059 NP_057143.1 Q9Y3C6 |
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