PPIF / Cyclophilin F

peptidylprolyl isomerase F

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in regulation of the mitochondrial permeability transition pore (mPTP). It is proposed that its association with the mPTP is masking a binding site for inhibiting inorganic phosphate (Pi) and promotes the open probability of the mPTP leading to apoptosis or necrosis; the requirement of the PPIase activity for this function is debated. In cooperation with mitochondrial TP53 is involved in activating oxidative stress-induced necrosis. Involved in modulation of mitochondrial membrane F1F0 ATP synthase activity and regulation of mitochondrial matrix adenine nucleotide levels. Has anti-apoptotic activity independently of mPTP and in cooperation with BCL2 inhibits cytochrome c-dependent apoptosis.

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Products

Proteins (10)

Type

Over-Expression Lysate (2)

Recombinant (8)

Target

PPIF / Cyclophilin F (10)

Publications

No (10)

Tag

GST (1)

GST, N-terminus (1)

His (2)

His, N-Terminal (1)

His-T7 (2)

Myc-DDK (Flag) (3)

Species

Human (7)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (5)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (1)

Biologically Active

Biologically active (1)

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Human PPIF / Cyclophilin F Protein (Recombinant His) - LS-G3522

Source:

E. coli

Tag:

His

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

100 µg/$317; 500 µg/$526; 20 µg/$245

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PPIF / Cyclophilin F Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115772

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

22.04 kDa

Price:

100 µg/$494

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Human PPIF / Cyclophilin F Protein (Recombinant His, N-Terminal) - LS-G144197

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

18.8 kDa

Price:

50 µg/$419

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Rat PPIF / Cyclophilin F Protein (Recombinant His) - LS-G3342

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human PPIF / Cyclophilin F Protein (Recombinant His-T7) (aa45-196) - LS-G13969

Source:

E. coli

Tag:

His-T7

Molecular Weight:

20.2 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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Mouse PPIF / Cyclophilin F Protein (Recombinant His-T7) (aa44-192) - LS-G13972

Source:

E. coli

Tag:

His-T7

Molecular Weight:

19.9 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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Human PPIF / Cyclophilin F Protein (Recombinant GST) (Full Length) - LS-G31953

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

48.4 kDa

Price:

2 µg/$439

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Human PPIF / Cyclophilin F Protein (Recombinant GST, N-terminus) (aa120-207) - LS-G61375

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PPIF / Cyclophilin F Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66540

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.8 kDa

Price:

20 µg/$1,107

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Human PPIF / Cyclophilin F Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77953

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

22.04 kDa

Price:

20 µg/$150

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