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POU3F4 is a member of the POU-III class of neural transcription factors. This family member plays a role in inner ear development. The protein is thought to be involved in the mediation of epigenetic signals which induce striatal neuron-precursor differentiation. Mutations in this gene are associated with X chromosome-linked nonsyndromic mixed deafness.
Gene Name: | POU class 3 homeobox 4 |
Synonyms: | POU3F4, BRN4, BRAIN-4, BRN-4, OCT-9, OTF-9, OTF9, POU class 3 homeobox 4, Octamer-binding protein 9, DFN3, DFNX2 |
Target Sequences: | NM_000307 NP_000298.3 |
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