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PON3

paraoxonase 3

PON3 is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have been described; however, only one has been fully characterized.

Gene Name: paraoxonase 3
Synonyms: PON3, Paraoxonase 3, Paraoxanase-3, Serum paraoxonase/lactonase 3
Target Sequences: L48516 AAC41996.1 Q15166

Publications (1)

1
Disruption of paraoxonase 3 impairs proliferation and antioxidant defenses in human A549 cells and causes embryonic lethality in mice. Sarah L Kempster, Gusztav Belteki, Diana Licence, D Stephen Charnock-Jones, Gordon C S Smith. The Breast : official journal of the European Society of Mastology. 2012 Jan;302:E103-7. [Full Text Article] [PubMed:21952037] Related Antibodies: LS-C38071.

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Products
Antibodies (49)
Primary (49)
PON3 (49)
Human (49)
Mouse (8)
Rat (8)
Bovine (6)
Dog (6)
Rabbit (6)
Sheep (3)
IHC (21)
IHC-P (8)
WB (45)
Flo (7)
ELISA (9)
Peptide-ELISA (1)
rabbit (36)
mouse (12)
goat (1)
Product Group
IHCPlus (1)
IgG (21)
IgG1 (10)
IgG2b (2)
monoclonal mc (12)
polyclonal pc (37)
OTI1A5 (2)
OTI1B12 (2)
OTI1F12 (2)
OTI4H9 (2)
OTI5B5 (2)
OTI5C3 (2)
APC (1)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (6)
Carrier-free (6)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (3)
Unconjugated (23)
aa30-319 (12)
aa2-354 (8)
aa10-38 (7)
C-Terminus (4)
aa143-192 (4)
aa1-354 (1)
aa185-346 (1)
aa30-354 (1)
No (48)
Yes (1)
PON3 Antibody - Western analysis of Lysates from human Serum, human A549 and HepG2 cells, mouse liver and spleen tissue and rat liver tissue
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PON3 Goat anti-Human Polyclonal (aa30-354) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$930
PON3 Antibody - Formalin-fixed and paraffin-embedded human hepatocarcinoma with PON3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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PON3 Rabbit anti-Human Polyclonal (aa10-38) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
PON3 Antibody - Anti-PON3 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PON3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
PON3 Antibody - Anti-PON3 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PON3 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
PON3 Antibody - Anti-PON3 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PON3 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
PON3 Antibody - Anti-PON3 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PON3 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
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PON3 Rabbit anti-Human Polyclonal (aa10-38) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
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PON3 Rabbit anti-Human Polyclonal (aa10-38) (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
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PON3 Rabbit anti-Human Polyclonal (aa10-38) (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
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PON3 Rabbit anti-Human Polyclonal (aa10-38) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
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PON3 Rabbit anti-Human Polyclonal (aa10-38) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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PON3 Rabbit anti-Human Polyclonal (aa10-38) (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
PON3 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-PON3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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PON3 Mouse anti-Human Monoclonal (aa30-319) (OTI5C3) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
PON3 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-PON3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
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PON3 Mouse anti-Human Monoclonal (aa30-319) (Carrier-free) (OTI5C3) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PON3 Antibody - Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-PON3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:2000)
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PON3 Mouse anti-Human Monoclonal (aa30-319) (OTI1A5) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
PON3 Antibody - Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-PON3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:2000)
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PON3 Mouse anti-Human Monoclonal (aa30-319) (Carrier-free) (OTI1A5) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PON3 Antibody - Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-PON3 mouse monoclonal antibody.This figure shows negative staining. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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PON3 Mouse anti-Human Monoclonal (aa30-319) (OTI1B12) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
PON3 Antibody - Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-PON3 mouse monoclonal antibody.This figure shows negative staining. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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PON3 Mouse anti-Human Monoclonal (aa30-319) (Carrier-free) (OTI1B12) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PON3 Antibody - IHC of paraffin-embedded Human liver tissue using anti-PON3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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PON3 Mouse anti-Human Monoclonal (aa30-319) (OTI1F12) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
PON3 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-PON3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
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PON3 Mouse anti-Human Monoclonal (aa30-319) (Carrier-free) (OTI1F12) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PON3 Antibody
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PON3 Rabbit anti-Human Polyclonal (aa185-346) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
PON3 Antibody - Immunohistochemistry image at a dilution of 1:200 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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PON3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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PON3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
PON3 Antibody - Western blot analysis of PON3 using LOVO cells whole cells lysates
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PON3 Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PON3 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PON3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PON3.
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PON3 Mouse anti-Human Monoclonal (aa30-319) (OTI5B5) Antibody
Human
WB
Unconjugated
100 µl/$434
Viewing 1-25 of 49 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).