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POLR3H

polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.

Gene Name: polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
Synonyms: POLR3H, KIAA1665, RNA polymerase III subunit C8, RPC22.9, RPC8
Target Sequences: NP_001018062.1 Q9Y535

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Products
Proteins (9)
Over-Expression Lysate (6)
Recombinant (3)
POLR3H (9)
No (9)
GST (1)
His (1)
Myc-DDK (Flag) (7)
Human (6)
293T Cells (3)
E. coli (1)
HEK 293 Cells (4)
Wheat Germ Extract (1)
Purified (2)
POLR3H Protein - Purified recombinant protein POLR3H was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
22.7 kDa
20 µg/$1,107
POLR3H Protein - 12.5% SDS-PAGE of human POLR3H stained with Coomassie Blue
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Wheat Germ Extract
GST
48.84 kDa
10 µg/$479; 25 µg/$670
POLR3H Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
22.7 kDa
20 µg/$150
POLR3H Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
19.5 kDa
20 µg/$150
POLR3H Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
22.7 kDa
20 µg/$150
POLR3H Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
22.7 kDa
100 µg/$494
POLR3H Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
19.5 kDa
100 µg/$494
POLR3H Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
22.7 kDa
100 µg/$494
POLR3H Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Viewing 1-9 of 9 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).