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POLR3H

polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.

Gene Name: polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
Synonyms: POLR3H, KIAA1665, RNA polymerase III subunit C8, RPC22.9, RPC8
Target Sequences: NP_001018062.1 Q9Y535

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Products
Antibodies (20)
Primary (20)
POLR3H (20)
Human (20)
Mouse (14)
Rat (7)
Bovine (1)
Chimpanzee (3)
Dog (3)
Monkey (4)
Rabbit (3)
IHC (4)
IHC-P (2)
WB (19)
Flo (7)
ELISA (7)
ICC (1)
IF (2)
Peptide-ELISA (2)
rabbit (16)
mouse (4)
IgG (10)
IgG1 (2)
IgG2a (2)
monoclonal mc (4)
polyclonal pc (16)
OTI4D8 (2)
OTI5A12 (2)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
Carrier-free (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (12)
aa5-33 (7)
C-Terminus (5)
120-200 aa, C-terminal (1)
aa151-200 (1)
No (20)
POLR3H Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-POLR3H mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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POLR3H Mouse anti-Human Monoclonal (OTI4D8) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
POLR3H Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-POLR3H mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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POLR3H Mouse anti-Human Monoclonal (Carrier-free) (OTI4D8) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
POLR3H Antibody - Immunochemical staining of human POLR3H in human brain with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
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POLR3H Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC-P
Unconjugated
100 µl/$412
POLR3H Antibody - Western blot of POLR3H antibody
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POLR3H Rabbit anti-Human Polyclonal (120-200 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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POLR3H Rabbit anti-Human Polyclonal (aa5-33) Antibody
Mouse, Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
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POLR3H Rabbit anti-Human Polyclonal (aa5-33) (Biotin) Antibody
Mouse, Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
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POLR3H Rabbit anti-Human Polyclonal (aa5-33) (FITC) Antibody
Mouse, Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
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POLR3H Rabbit anti-Human Polyclonal (aa5-33) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
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POLR3H Rabbit anti-Human Polyclonal (aa5-33) (APC) Antibody
Mouse, Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
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POLR3H Rabbit anti-Human Polyclonal (aa5-33) (PE) Antibody
Mouse, Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
POLR3H Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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POLR3H Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
POLR3H Antibody - Immunohistochemical analysis of POLR3H staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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POLR3H Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Bovine, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
POLR3H Antibody - Western blot of RPC8 Antibody in mouse testis tissue lysates (35 ug/lane). RPC8 (arrow) was detected using the purified antibody.
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POLR3H Rabbit anti-Human Polyclonal (aa5-33) Antibody
Mouse, Human
Flo, WB
Unconjugated
400 µl/$393
POLR3H Antibody - Western blot analysis of lysates from K562 cells, using RPC8 Antibody. The lane on the right is blocked with the synthesized peptide.
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POLR3H Rabbit anti-Human Polyclonal (aa151-200) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
POLR3H Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY POLR3H. (Right lane) cDNA for 48 hrs and lysed
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POLR3H Mouse anti-Human Monoclonal (OTI5A12) Antibody
Human
WB
Unconjugated
100 µl/$434
POLR3H Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY POLR3H. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-POLR3H. (1:2000)
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POLR3H Mouse anti-Human Monoclonal (Carrier-free) (OTI5A12) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
POLR3H Antibody - POLR3H antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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POLR3H Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
POLR3H Antibody - POLR3H antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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POLR3H Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Rabbit, Mouse, Dog, Rat, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
POLR3H Antibody - POLR3H antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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POLR3H Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Rabbit, Mouse, Dog, Rat, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
POLR3H Antibody - POLR3H antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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POLR3H Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Rabbit, Mouse, Dog, Rat, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).