POLH / DNA Polymerase Eta

polymerase (DNA directed), eta

DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci.

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Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

POLH / DNA Polymerase Eta (4)

Publications

No (4)

Tag

GST (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human POLH / DNA Polymerase Eta Protein (Recombinant GST) (Full Length) - LS-G29801

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

71.28 kDa

Price:

10 µg/$479; 25 µg/$670

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Human POLH / DNA Polymerase Eta Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71336

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

78.2 kDa

Price:

20 µg/$1,107

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Human POLH / DNA Polymerase Eta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89513

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

78.2 kDa

Price:

20 µg/$215

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POLH / DNA Polymerase Eta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115265

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

78.2 kDa

Price:

100 µg/$710

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