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POFUT2

protein O-fucosyltransferase 2

Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin (TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition (EMT), maintaining the correct patterning of mesoderm and localization of the definite endoderm (By similarity). Required for the proper secretion of ADAMTS family members such as ADAMSL1 and ADAMST13.

Gene Name: protein O-fucosyltransferase 2
Synonyms: POFUT2, C21orf80, KIAA0958, FUT13, Protein O-fucosyltransferase 2, O-FucT-2, Peptide-O-fucosyltransferase 2
Target Sequences: NM_015227 NP_056042.1 Q9Y2G5

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Products
Proteins (6)
Over-Expression Lysate (4)
Recombinant (2)
POFUT2 (6)
No (6)
GST (1)
Myc-DDK (Flag) (5)
Human (4)
293T Cells (2)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (1)
POFUT2 Protein - Purified recombinant protein POFUT2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
49.8 kDa
20 µg/$1,107
POFUT2 Protein - 12.5% SDS-PAGE of human POFUT2 stained with Coomassie Blue
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Wheat Germ Extract
GST
76.4 kDa
10 µg/$479; 25 µg/$670
POFUT2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
48.7 kDa
20 µg/$215
POFUT2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
49.8 kDa
20 µg/$150
POFUT2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
48.7 kDa
100 µg/$710
POFUT2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
49.8 kDa
100 µg/$494
Viewing 1-6 of 6 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).