POFUT1

protein O-fucosyltransferase 1

Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue found in the consensus sequence C2-X(4,5)-[S/T]-C3 of EGF domains, where C2 and C3 are the second and third conserved cysteines. Specifically uses GDP-fucose as donor substrate and proper disulfide pairing of the substrate EGF domains is required for fucose transfer. Plays a crucial role in NOTCH signaling. Initial fucosylation of NOTCH by POFUT1 generates a substrate for FRINGE/RFNG, an acetylglucosaminyltransferase that can then extend the fucosylation on the NOTCH EGF repeats. This extended fucosylation is required for optimal ligand binding and canonical NOTCH signaling induced by DLL1 or JAGGED1. Fucosylates AGRN and determines its ability to cluster acetylcholine receptors (AChRs).

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Products

Antibodies (38)

Type

Primary (38)

Target

POFUT1 (38)

Reactivity

Human (38)

Mouse (18)

Rat (8)

Bat (3)

Bovine (3)

Chimpanzee (3)

Dog (4)

Gibbon (3)

Guinea pig (3)

Hamster (3)

Horse (3)

Monkey (4)

Orangutan (3)

Pig (4)

Rabbit (3)

Zebrafish (3)

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Application

IHC (16)

IHC-P (3)

WB (37)

ELISA (12)

ICC (2)

IF (3)

IP (3)

Peptide-ELISA (2)

Host

rabbit (38)

Isotype

IgG (15)

Clonality

polyclonal pc (38)

Format

APC (2)

APC Conjugated (3)

Azide-free (1)

Biotin Conjugated (4)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (3)

Unconjugated (16)

Epitope

aa238-388 (8)

aa243-393 (8)

aa344-373 (7)

aa101-150 (4)

300-380 aa, C-terminal (1)

C-Terminus (1)

aa17-180 (1)

aa331-380 (1)

Publications

No (38)

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POFUT1 Antibody (aa17-180) LS-C179093

Antibody:

POFUT1 Rabbit anti-Human Polyclonal (aa17-180) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µl/$332

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POFUT1 Antibody (C-Terminus) LS-C353355

Antibody:

POFUT1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Dog, Pig, Human, Monkey

Applications:

ICC, IF, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

30 µl/$255; 50 µl/$271; 100 µl/$299; 200 µl/$351

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POFUT1 Antibody LS-C753105

Antibody:

POFUT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

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POFUT1 Antibody LS-C805079

Antibody:

POFUT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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POFUT1 Antibody (aa331-380) LS-C120002

Antibody:

POFUT1 Rabbit anti-Human Polyclonal (aa331-380) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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POFUT1 Antibody (300-380 aa, C-terminal) LS-C385014

Antibody:

POFUT1 Rabbit anti-Human Polyclonal (300-380 aa, C-terminal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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POFUT1 Antibody (aa344-373) LS-C324154

Antibody:

POFUT1 Rabbit anti-Human Polyclonal (aa344-373) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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POFUT1 Antibody (aa344-373, Biotin) LS-C266682

Antibody:

POFUT1 Rabbit anti-Human Polyclonal (aa344-373) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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POFUT1 Antibody (aa344-373, FITC) LS-C266683

Antibody:

POFUT1 Rabbit anti-Human Polyclonal (aa344-373) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

POFUT1 Antibody (aa344-373, Azide-free, HRP) LS-C266684

Antibody:

POFUT1 Rabbit anti-Human Polyclonal (aa344-373) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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POFUT1 Antibody (aa344-373, APC) LS-C266681

Antibody:

POFUT1 Rabbit anti-Human Polyclonal (aa344-373) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

POFUT1 Antibody (aa344-373, PE) LS-C266686

Antibody:

POFUT1 Rabbit anti-Human Polyclonal (aa344-373) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

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POFUT1 Antibody (aa238-388) LS-C374307

Antibody:

POFUT1 Rabbit anti-Human Polyclonal (aa238-388) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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POFUT1 Antibody LS-C83909

Antibody:

POFUT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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POFUT1 Antibody LS-C824142

Antibody:

POFUT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

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POFUT1 Antibody (aa344-373) LS-C163834

Antibody:

POFUT1 Rabbit anti-Human Polyclonal (aa344-373) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

POFUT1 Antibody LS-C832080

Antibody:

POFUT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

POFUT1 Antibody (aa243-393) LS-C374311

Antibody:

POFUT1 Rabbit anti-Mouse Polyclonal (aa243-393) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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POFUT1 Antibody (aa243-393, Biotin) LS-C686715

Antibody:

POFUT1 Rabbit anti-Mouse Polyclonal (aa243-393) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

Select

POFUT1 Antibody (aa243-393, FITC) LS-C693460

Antibody:

POFUT1 Rabbit anti-Mouse Polyclonal (aa243-393) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765

Select

POFUT1 Antibody (aa243-393, Cy3) LS-C701970

Antibody:

POFUT1 Rabbit anti-Mouse Polyclonal (aa243-393) (Cy3) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

Select

POFUT1 Antibody (aa243-393, PE) LS-C725052

Antibody:

POFUT1 Rabbit anti-Mouse Polyclonal (aa243-393) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

• Unconjugated
• Biotin
• FITC
• Cy3
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • Cy3
  • PE

Select

POFUT1 Antibody (aa101-150) LS-C135521

Antibody:

POFUT1 Rabbit anti-Human Polyclonal (aa101-150) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

POFUT1 Antibody LS-C817008

Antibody:

POFUT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$412

Select

POFUT1 Antibody LS-C409874

Antibody:

POFUT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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