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PODXL / Podocalyxin

podocalyxin-like

Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up inital epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells.

Gene Name: podocalyxin-like
Synonyms: PODXL, GCTM-2 antigen, gp200, PCLP, PCLP-1, PCLP1, Podocalyxin-like protein 1, Podocalyxin, Podocalyxin-like, TRA-1-60, TRA-1-81
Target Sequences: NM_005397 NP_005388.2 O00592

☰ Filters
Products
Proteins (11)
Over-Expression Lysate (2)
Recombinant (9)
PODXL / Podocalyxin (11)
No (11)
6His, N-terminus (3)
DDK (Flag)-His, C-terminus (2)
His, N-Terminal (1)
His-GST (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (7)
Mouse (1)
Rat (2)
293T Cells (1)
E. coli (4)
HEK 293 Cells (4)
Yeast (2)
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Yeast
6His, N-terminus
46.2 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
PODXL / Podocalyxin Protein
Select
Yeast
6His, N-terminus
39.82 kD
100 µg/$499; 20 µg/$364; 1 mg/$1,683
Select
E. coli
6His, N-terminus
48.3 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
PODXL / Podocalyxin Protein - Recombinant Podocalyxin By SDS-PAGE
Select
E. coli
His, N-Terminal
28.4 kDa
10 µg/$282; 50 µg/$447; 200 µg/$892; 1 mg/$2,005; 5 mg/$3,123; 2 mg/$2,192
PODXL / Podocalyxin Protein - Purified recombinant protein PODXL was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
53.1 kDa
20 µg/$1,107
PODXL / Podocalyxin Protein - Recombinant Podocalyxin By SDS-PAGE
Select
E. coli
His-GST
55.1 kDa
10 µg/$277; 50 µg/$412; 100 µg/$660; 200 µg/$825; 1 mg/$1,910; 500 µg/$1,460; 5 mg/$2,885; 2 mg/$2,095
PODXL / Podocalyxin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
55.39 kDa
20 µg/$150
PODXL / Podocalyxin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
55.39 kDa
100 µg/$494
PODXL / Podocalyxin Protein
Select
HEK 293 Cells
DDK (Flag)-His, C-terminus
44 kda
20 µg/$1,107
PODXL / Podocalyxin Protein
Select
HEK 293 Cells
DDK (Flag)-His, C-terminus
47.7 kDa
20 µg/$1,107
PODXL / Podocalyxin Protein - Recombinant Podocalyxin By SDS-PAGE
Select
E. coli
His-T7
28.9 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).