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PNMT catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene.
Gene Name: | phenylethanolamine N-methyltransferase |
Synonyms: | PNMT, PNMTase, PENT, Phenylethanolamine N-methylase |
Target Sequences: | NM_002686 NP_002677.1 P11086 |
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