Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
PMVK encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of this protein is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis.
Gene Name: | phosphomevalonate kinase |
Synonyms: | PMVK, PMKA, PMKASE, PMKI, HPMK, HUMPMKI, Phosphomevalonate kinase, PMK |
Target Sequences: | NM_006556 NP_006547.1 Q15126 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.