PMAIP1 / NOXA

phorbol-12-myristate-13-acetate-induced protein 1

Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 By similarity. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

PMAIP1 / NOXA (6)

Publications

No (6)

Tag

6His, N-terminus (1)

GST (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (1)

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Human PMAIP1 / NOXA Protein (Recombinant 6His, N-terminus) (Pro2-Asn136) - LS-G26639

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

16 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365

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Human PMAIP1 / NOXA Protein (Recombinant GST) (Full Length) - LS-G29779

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

40.7 kDa

Price:

2 µg/$439

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Human PMAIP1 / NOXA Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67967

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

5.8 kDa

Price:

20 µg/$1,107

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Human PMAIP1 / NOXA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81103

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

5.8 kDa

Price:

20 µg/$150

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PMAIP1 / NOXA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101726

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

5.8 kDa

Price:

100 µg/$494

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Human PMAIP1 / NOXA Protein (Recombinant His) (aa1-136) - LS-G140983

Source:

E. coli

Sequence Length:

135 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

14.96 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

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