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PMAIP1 / NOXA
phorbol-12-myristate-13-acetate-induced protein 1
Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 By similarity. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
| Gene Name: | phorbol-12-myristate-13-acetate-induced protein 1 |
| Family/Subfamily: | Apoptosis , not assigned-Other |
| Synonyms: | PMAIP1, NOXA, PMA-induced protein 1, Protein Noxa, APR |
| Target Sequences: | NM_021127 NP_066950.1 Q13794 |
Publications (1)
1
Unique characteristics of radiation-induced apoptosis in the postnatally developing small intestine and colon of mice. Miyoshi-Imamura T, Kakinuma S, Kaminishi M, Okamoto M, Takabatake T, Nishimura Y, Imaoka T, Nishimura M, Murakami-Murofushi K, Shimada Y. Radiation research. 2010 173:310-8. (IHC-P; Mouse)
[PubMed:20199216]
Related Antibodies: LS-B184.
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Products
Antibodies
(27)
Type
Primary
(27)
Target
PMAIP1 / NOXA
(27)
Reactivity
Human
(23)
Mouse
(13)
Rat
(9)
Monkey
(1)
Application
IHC
(5)
IHC-P
(5)
WB
(22)
ELISA
(8)
ICC
(2)
IF
(3)
Peptide-ELISA
(2)
Host
rabbit
(17)
mouse
(5)
goat
(2)
rat
(3)
Product Group
IHCPlus
(3)
Isotype
IgG
(15)
IgG1
(2)
IgG1,k
(3)
IgG2b,k
(3)
Clonality
monoclonal mc
(8)
polyclonal pc
(19)
Clone
114C307.1
(4)
69N15C9
(2)
ABM16G6
(1)
Format
Azide-free
(2)
Biotin Conjugated
(3)
FITC Conjugated
(2)
HRP Conjugated
(2)
PE Conjugated
(1)
Unconjugated
(19)
Epitope
aa1-103
(2)
N-Terminus
(1)
aa1-16
(1)
aa27-41
(1)
aa51-66
(1)
aa75-90
(1)
Publications
No
(26)
Yes
(1)
PMAIP1 / NOXA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
PMAIP1 / NOXA Rabbit anti-Mouse Polyclonal (aa51-66) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
PMAIP1 / NOXA Mouse anti-Human Monoclonal (114C307.1) Antibody
Human
ELISA, ICC, WB
Unconjugated
100 µg/$813
PMAIP1 / NOXA Goat anti-Human Polyclonal (aa27-41) Antibody
Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
PMAIP1 / NOXA Mouse anti-Human Monoclonal (Biotin) (114C307.1) Antibody
Mouse, Human
ELISA
Biotin Conjugated
0.1 ml/$416
PMAIP1 / NOXA Mouse anti-Human Monoclonal (114C307.1) Antibody
Human
WB
Unconjugated
100 µg/$386
PMAIP1 / NOXA Mouse anti-Human Monoclonal (Azide-free) (114C307.1) Antibody
Mouse, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated, Azide-free
0.1 mg/$386
PMAIP1 / NOXA Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
PMAIP1 / NOXA Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
PMAIP1 / NOXA Rabbit anti-Human Polyclonal Antibody
Human
IHC-P, WB
Unconjugated
50 µl/$460
PMAIP1 / NOXA Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µg/$649
PMAIP1 / NOXA Goat anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
0.1 mg/$579
PMAIP1 / NOXA Mouse anti-Human Monoclonal (ABM16G6) Antibody
Human
WB
Unconjugated
25 µg/$288; 100 µg/$414
PMAIP1 / NOXA Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PMAIP1 / NOXA Rabbit anti-Mouse Polyclonal (aa1-16) Antibody
Mouse, Rat
WB
Unconjugated
100 µl/$688
PMAIP1 / NOXA Rabbit anti-Mouse Polyclonal (aa75-90) Antibody
Mouse, Rat
WB
Unconjugated
100 µl/$688
PMAIP1 / NOXA Rat anti-Mouse Monoclonal (aa1-103) (69N15C9) Antibody
Mouse
WB
Unconjugated
0.1 mg/$386
![PMAIP1 / NOXA Antibody - Western Blot: Noxa Antibody (69N15C9) [Azide Free] - Analysis of mouse A) Noxa recombinant protein, B) thymus and C) ovary using Noxa antibody at 1 ug/ml, 5 ug/ml and 5 ug/ml, respectively. This image was taken for the unmodified form of this product. Other forms have not been tested.](https://lsbio-7d62.kxcdn.com/image2/pmaip1-noxa-antibody-aa1-103-clone-69n15c9-azide-free-ls-c366816/257430_1943533.jpg)
PMAIP1 / NOXA Rat anti-Mouse Monoclonal (aa1-103) (Azide-free) (69N15C9) Antibody
Mouse
WB
Unconjugated, Azide-free
0.1 mg/$386
PMAIP1 / NOXA Rat anti-Human Monoclonal Antibody
Human
WB
Unconjugated
25 µg/$288; 100 µg/$414
PMAIP1 / NOXA Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
PMAIP1 / NOXA Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
PMAIP1 / NOXA Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse, Rat, Human
WB
HRP Conjugated
100 µl/$1,006
PMAIP1 / NOXA Rabbit anti-Mouse Polyclonal (Biotin) Antibody
Mouse, Rat, Human
WB
Biotin Conjugated
100 µl/$1,006
PMAIP1 / NOXA Rabbit anti-Mouse Polyclonal (FITC) Antibody
Mouse, Rat, Human
WB
FITC Conjugated
100 µl/$1,006
PMAIP1 / NOXA Rabbit anti-Mouse Polyclonal (PE) Antibody
Mouse, Rat, Human
WB
PE Conjugated
100 µl/$1,006
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product results
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