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PLP1 / Myelin PLP

proteolipid protein 1

PLP1 / Myelin PLP is a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant.

Gene Name: proteolipid protein 1
Synonyms: PLP1, HLD1, PMD, Myelin proteolipid protein, Proteolipid protein 1, SPG2, Lipophilin, MMPL, PLP, PLP/DM20
Target Sequences: NM_000533 NP_000524.3

Publications (1)

1
Transient immune activation without loss of intraepidermal innervation and associated Schwann cells in patients with complex regional pain syndrome. Beate Hartmannsberger, Sabrina Scriba, Carolina Guidolin, Juliane Becker, Katharina Mehling, Kathrin Doppler, Claudia Sommer, Heike L Rittner. Journal of neuroinflammation. 2024 January;21:23. [Full Text Article] [PubMed:38233858] [PMC:PMC10792943]

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Products
Proteins (11)
Over-Expression Lysate (6)
Recombinant (5)
PLP1 / Myelin PLP (11)
No (11)
10His, N-terminus (1)
GST, N-terminus (1)
GST-His, N-terminus (1)
His (2)
Myc-DDK (Flag) (6)
Human (6)
Rainbow trout (2)
293T Cells (3)
E. coli (3)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Yeast (1)
Purified (1)
PLP1 / Myelin PLP Protein - Recombinant Proteolipid Protein 1, Myelin (PLP1) by SDS-PAGE
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E. coli
GST-His, N-terminus
16kDa
10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
PLP1 / Myelin PLP Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His, N-terminus
35.5 kDa
100 µg/$1,801; 20 µg/$1,247
PLP1 / Myelin PLP Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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E. coli
His
11.8 kD
1 mg/$1,679; 100 µg/$598; 20 µg/$405
PLP1 / Myelin PLP Protein
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Yeast
His
9.71 kD
100 µg/$679; 20 µg/$429; 1 mg/$1,973
PLP1 / Myelin PLP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
26.1 kDa
100 µg/$494
PLP1 / Myelin PLP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
29.9 kDa
100 µg/$494
PLP1 / Myelin PLP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
29.9 kDa
20 µg/$150
PLP1 / Myelin PLP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
29.9 kDa
20 µg/$150
PLP1 / Myelin PLP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
26.1 kDa
20 µg/$150
PLP1 / Myelin PLP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
29.9 kDa
100 µg/$494
Viewing 1-11 of 11 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).