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PLG / Plasmin / Plasminogen

plasminogen

Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.

Gene Name: plasminogen
Family/Subfamily: Protease , Serine S1
Synonyms: PLG, Plasmin, Plasminogen
Target Sequences: NM_000301 NP_000292.1 P00747

Publications (5)

1
Borrelia burgdorferi infection-associated surface proteins ErpP, ErpA, and ErpC bind human plasminogen. Brissette CA, Haupt K, Barthel D, Cooley AE, Bowman A, Skerka C, Wallich R, Zipfel PF, Kraiczy P, Stevenson B. Infection and immunity. 2009 77:300-6. [PubMed:19001079] [PMC:PMC2612283]
2
Roles for phagocytic cells and complement in controlling relapsing fever infection. Woodman ME, Cooley AE, Avdiushko R, Bowman A, Botto M, Wooten RM, van Rooijen N, Cohen DA, Stevenson B. Journal of leukocyte biology. 2009 86:727-36. [PubMed:19458267]
3
Functional characterization of Borrelia spielmanii outer surface proteins that interact with distinct members of the human factor H protein family and with plasminogen. Seling A, Siegel C, Fingerle V, Jutras BL, Brissette CA, Skerka C, Wallich R, Zipfel PF, Stevenson B, Kraiczy P. Infection and immunity. 2010 78:39-48. (ELISA; Human) [PubMed:19858303] [PMC:PMC2798189]
4
Leptospiral endostatin-like protein A is a bacterial cell surface receptor for human plasminogen. Verma A, Brissette CA, Bowman AA, Shah ST, Zipfel PF, Stevenson B. Infection and immunity. 2010 78:2053-9. (ELISA; Human) [PubMed:20160016] [PMC:PMC2863546]
5
Borrelia burgdorferi enolase is a surface-exposed plasminogen binding protein. Floden AM, Watt JA, Brissette CA. PloS one. 2011 6:e27502. [PubMed:22087329] [PMC:PMC3210797]
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☰ Filters
Products
Proteins (13)
Over-Expression Lysate (2)
Recombinant (11)
PLG / Plasmin / Plasminogen (13)
No (13)
6His, N-terminus (1)
GST (1)
GST, N-terminus (1)
His (4)
His, N-Terminal (2)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (9)
Mouse (1)
Rat (2)
293T Cells (1)
E. coli (7)
Eukaryotic cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Yeast (1)
Purified (3)
Biologically active (1)
PLG / Plasmin / Plasminogen Protein
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E. coli
None
Biologically active
29.7 kDa
10 µg/$282; 100 µg/$514; 500 µg/$1,098
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E. coli
His
10 µg/$239; 50 µg/$283; 100 µg/$326; 200 µg/$362; 1 mg/$1,065; 500 µg/$722; 5 mg/$1,858; 2 mg/$1,200
PLG / Plasmin / Plasminogen Protein - 12.5% SDS-PAGE of human PLG stained with Coomassie Blue
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Wheat Germ Extract
GST
117 kDa
2 µg/$439
PLG / Plasmin / Plasminogen Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
90.58 kDa
20 µg/$150
PLG / Plasmin / Plasminogen Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PLG / Plasmin / Plasminogen Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
90.58 kDa
100 µg/$494
PLG / Plasmin / Plasminogen Protein - Active Plasminogen (Plg) by WB
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E. coli
His, N-Terminal
38kDa
10 µg/$323; 50 µg/$702; 200 µg/$1,298; 100 µg/$1,096; 1 mg/$2,562; 500 µg/$2,060; 5 mg/$4,901; 2 mg/$2,753
PLG / Plasmin / Plasminogen Protein - Eukaryotic Plasminogen (Plg) by SDS-PAGE
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Eukaryotic cells
His, N-Terminal
30kDa
10 µg/$294; 50 µg/$522; 200 µg/$1,034; 100 µg/$832; 1 mg/$2,192; 500 µg/$1,712; 5 mg/$3,641; 2 mg/$2,383
PLG / Plasmin / Plasminogen Protein
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Yeast
His
30.4 kDa
10 µg/$315; 50 µg/$522; 100 µg/$782
PLG / Plasmin / Plasminogen Protein - Recombinant Plasminogen By SDS-PAGE
Select
E. coli
His
33.5 kDa
10 µg/$239; 50 µg/$283; 100 µg/$326; 200 µg/$362; 1 mg/$1,065; 500 µg/$722; 5 mg/$1,858; 2 mg/$1,200
PLG / Plasmin / Plasminogen Protein - Recombinant Plasminogen By SDS-PAGE
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E. coli
His-T7
31.4 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
PLG / Plasmin / Plasminogen Protein - Recombinant Plasminogen By SDS-PAGE
Select
E. coli
His
26.8 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
PLG / Plasmin / Plasminogen Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
6His, N-terminus
36.0 kDa
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Viewing 1-13 of 13 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).