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PLG / Plasmin / Plasminogen

plasminogen

Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.

Gene Name: plasminogen
Family/Subfamily: Protease , Serine S1
Synonyms: PLG, Plasmin, Plasminogen
Target Sequences: NM_000301 NP_000292.1 P00747

Publications (5)

1
Borrelia burgdorferi infection-associated surface proteins ErpP, ErpA, and ErpC bind human plasminogen. Brissette CA, Haupt K, Barthel D, Cooley AE, Bowman A, Skerka C, Wallich R, Zipfel PF, Kraiczy P, Stevenson B. Infection and immunity. 2009 77:300-6. [PubMed:19001079] [PMC:PMC2612283]
2
Roles for phagocytic cells and complement in controlling relapsing fever infection. Woodman ME, Cooley AE, Avdiushko R, Bowman A, Botto M, Wooten RM, van Rooijen N, Cohen DA, Stevenson B. Journal of leukocyte biology. 2009 86:727-36. [PubMed:19458267]
3
Functional characterization of Borrelia spielmanii outer surface proteins that interact with distinct members of the human factor H protein family and with plasminogen. Seling A, Siegel C, Fingerle V, Jutras BL, Brissette CA, Skerka C, Wallich R, Zipfel PF, Stevenson B, Kraiczy P. Infection and immunity. 2010 78:39-48. (ELISA; Human) [PubMed:19858303] [PMC:PMC2798189]
4
Leptospiral endostatin-like protein A is a bacterial cell surface receptor for human plasminogen. Verma A, Brissette CA, Bowman AA, Shah ST, Zipfel PF, Stevenson B. Infection and immunity. 2010 78:2053-9. (ELISA; Human) [PubMed:20160016] [PMC:PMC2863546]
5
Borrelia burgdorferi enolase is a surface-exposed plasminogen binding protein. Floden AM, Watt JA, Brissette CA. PloS one. 2011 6:e27502. [PubMed:22087329] [PMC:PMC3210797]
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Products
ELISA Kits (40)
Competitive EIA (6)
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PLG / Plasmin / Plasminogen (40)
Human (13)
Mouse (5)
Rat (8)
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Canine (1)
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Guinea pig (1)
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12 x 8-Well Microstrips (1)
96-Well Microplate (4)
96-Well Strip Plate (31)
Antibody Pair and Standard (3)
No (40)
Cell Culture Media (2)
Cell Culture Supernatants (9)
Cell Lysates (6)
EDTA Plasma (1)
Heparin Plasma (1)
Plasma (33)
Serum (34)
Tissue Extracts (2)
Tissue Homogenates (15)
Urine (2)
PLG / Plasmin / Plasminogen ELISA Kit
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Sandwich
96-Well Microplate
Human
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
PLG / Plasmin / Plasminogen ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
15.63 - 1000 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$750
PLG / Plasmin / Plasminogen ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
1 - 500 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Media, Plasma, Serum, Tissue Extracts, Urine
1 Plate/$698
PLG / Plasmin / Plasminogen ELISA Kit
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Sandwich
96-Well Microplate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
PLG / Plasmin / Plasminogen ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
PLG / Plasmin / Plasminogen ELISA Kit
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Competitive EIA
96-Well Strip Plate
Rabbit
62.5 - 4000 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$870
PLG / Plasmin / Plasminogen ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.5 - 500 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Media, Plasma, Serum, Tissue Extracts, Urine
1 Plate/$565
PLG / Plasmin / Plasminogen ELISA Kit
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Competitive EIA
96-Well Strip Plate
Bovine
0.469 - 30 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
PLG / Plasmin / Plasminogen ELISA Kit
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Sandwich
96-Well Strip Plate
Guinea pig
15.625 - 1000 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
PLG / Plasmin / Plasminogen ELISA Kit
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Sandwich
96-Well Strip Plate
Bovine
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$816
PLG / Plasmin / Plasminogen ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$816
PLG / Plasmin / Plasminogen ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$685
PLG / Plasmin / Plasminogen ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
2.5 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
PLG / Plasmin / Plasminogen ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
PLG / Plasmin / Plasminogen ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
7.8 - 500 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
PLG / Plasmin / Plasminogen ELISA Kit
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Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
PLG / Plasmin / Plasminogen ELISA Kit
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Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
PLG / Plasmin / Plasminogen ELISA Kit
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Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$783
PLG / Plasmin / Plasminogen ELISA Kit
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Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$585
PLG / Plasmin / Plasminogen ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
125 - 8000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
PLG / Plasmin / Plasminogen ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
31.25 - 2000 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
PLG / Plasmin / Plasminogen ELISA Kit
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Sandwich
96-Well Strip Plate
Human
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
PLG / Plasmin / Plasminogen ELISA Kit
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Sandwich
96-Well Strip Plate
Canine
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
PLG / Plasmin / Plasminogen ELISA Kit
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Sandwich CLIA
96-Well Strip Plate
Rat
1.563 - 100 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
PLG / Plasmin / Plasminogen ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
78.125 - 5000 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).