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PLCG2 / PLC Gamma 2

phospholipase C, gamma 2 (phosphatidylinositol-specific)

PLCG2 / PLC Gamma 2 is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.

Gene Name: phospholipase C, gamma 2 (phosphatidylinositol-specific)
Family/Subfamily: Phospholipase , not assigned-Phospholipase
Synonyms: PLCG2, FCAS3, Phospholipase C-gamma-2, PLCG 2, PLC-IV, APLAID, Phospholipase C-IV, PLC-gamma-2
Target Sequences: NM_002661 NP_002652.2 P16885

☰ Filters
Antibodies (55)
ELISA Kits (15)
Proteins (5)
Cell-Based (1)
Cell-Based Phosphorylation (2)
Custom (3)
Over-Expression Lysate (2)
Primary (55)
Recombinant (3)
Sandwich (8)
Sandwich CLIA (1)
PLCG2 / PLC Gamma 2 (75)
Human (62)
Mouse (40)
Rat (34)
Bovine (4)
Chicken (5)
Chimpanzee (3)
Dog (4)
Horse (4)
Monkey (8)
Porcine (1)
Rabbit (5)
Sheep (1)
IHC (26)
IHC-P (11)
WB (50)
Flo (2)
ELISA (13)
IF (7)
IP (4)
Peptide-ELISA (6)
rabbit (52)
mouse (3)
Product Group
IHCPlus (1)
IgG (26)
IgG1 (2)
IgG2b (1)
monoclonal mc (3)
polyclonal pc (52)
1E10C11 (1)
2D9E8 (1)
3A8B6 (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (4)
96-Well Strip Plate (10)
APC (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (45)
aa930-1152 (8)
pTyr1217 (8)
pTyr753 (7)
aa619-668 (4)
C-Terminus (3)
pTyr759 (3)
1160-1240 aa (2)
690-770 aa (1)
Arg747 (1)
Internal (1)
aa1186-1235 (1)
aa721-770 (1)
p1217 (1)
p753 (1)
No (75)
Adherent Cell Cultures (3)
Cell Lysates (1)
Plasma (3)
Serum (3)
Tissue Homogenates (2)
His (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Low endotoxin level (1)
PLCG2 / PLC Gamma 2 Antibody - Immunohistochemistry of paraffin-embedded mouse heart.
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PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, IP, WB
Unconjugated
20 µl/$275; 100 µl/$389
PLCG2 / PLC Gamma 2 Antibody - Immunohistochemistry analysis of paraffin-embedded human brain, using PLCG2 (Phospho-Tyr1217) Antibody. The picture on the right is blocked with the phospho peptide.
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PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (pTyr1217) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PLCG2 / PLC Gamma 2 ELISA Kit
Select
Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
PLCG2 / PLC Gamma 2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
PLCG2 / PLC Gamma 2 ELISA Kit
Select
Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
PLCG2 / PLC Gamma 2 Protein - Purified recombinant protein PLCG2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
147.7 kDa
20 µg/$1,107
PLCG2 / PLC Gamma 2 Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using PLCG2 (Phospho-Tyr753) Antibody. The picture on the right is blocked with the phospho peptide.
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PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (pTyr753) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PLCG2 / PLC Gamma 2 Antibody - Immunohistochemical analysis of PLC gamma 2 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$299
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PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (pTyr1217) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Horse, Human, Monkey
IHC
Unconjugated
100 µg/$570
PLCG2 / PLC Gamma 2 Antibody - Anti-PLCG2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (aa721-770) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
PLCG2 / PLC Gamma 2 Antibody - Western blot analysis of PLC gamma 2 (pY759) expression in HeLa (A); NIH3T3 (B); H9C2 (C) whole cell lysates.
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PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (pTyr759) Antibody
Mouse, Rat, Human, Monkey
WB
Unconjugated
100 µl/$315
PLCG2 / PLC Gamma 2 Antibody - 1:200 staining human lymph node tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (pTyr753) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PLCG2 / PLC Gamma 2 Antibody - IHC analysis of PLCG 2 using anti-PLCG 2 antibody. PLCG 2 was detected in paraffin-embedded section of rat spleen tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 2µg/ml rabbit anti-PLCG 2 Antibody overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
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PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (1160-1240 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PLCG2 / PLC Gamma 2 Antibody - 1:100 staining human prostate tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PLCG2 / PLC Gamma 2 Antibody - P-peptide - + Immunohistochemistry analysis of paraffin-embedded human tonsil tissue using PLCG2 (Phospho-Tyr1217) antibody.
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PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (pTyr1217) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
PLCG2 / PLC Gamma 2 ELISA Kit
Select
Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
PLCG2 / PLC Gamma 2 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
PLCG2 / PLC Gamma 2 Protein - Recombinant Phospholipase C Gamma 2, Phosphatidylinositol Specific By SDS-PAGE
Select
E. coli
His-T7
29.3 kDa
10 µg/$279; 50 µg/$430; 100 µg/$687; 200 µg/$857; 1 mg/$1,956; 500 µg/$1,499; 5 mg/$2,997; 2 mg/$2,142
PLCG2 / PLC Gamma 2 Antibody - Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PLCG2 Antibody. The picture on the right is blocked with the synthesized peptide.
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PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (aa1186-1235) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
PLCG2 / PLC Gamma 2 Mouse anti-Human Monoclonal (1E10C11) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$459
Select
PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (1160-1240 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PLCG2 / PLC Gamma 2 Antibody - Western blot of Phospho-PLC gamma2 (Y753) antibody
Select
PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (690-770 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Horse, Human, Monkey
IF, IHC
Unconjugated
50 µg/$489
PLCG2 / PLC Gamma 2 Antibody - Peptide - + Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using PLCG2 (Ab-753) antibody.
Select
PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (p753) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
Viewing 1-25 of 75 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).