PLAU / Urokinase / uPA

plasminogen activator, urokinase

PLAU / Urokinase / uPA is a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Products

ELISA Kits (42)

Type

Custom (3)

Functional (3)

Sandwich (31)

Sandwich CLIA (5)

Target

PLAU / Urokinase / uPA (42)

Reactivity

Human (12)

Mouse (8)

Rat (9)

Bovine (1)

Chicken (2)

Guinea pig (1)

Horse (1)

Monkey (2)

Pig (2)

Porcine (1)

Rabbit (2)

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Format

12 x 8-Well Microstrips (4)

96-Well Microplate (8)

96-Well Strip Plate (30)

Publications

No (42)

Sample Type

Cell Culture Media (2)

Cell Culture Supernatants (6)

Cell Lysates (3)

Plasma (36)

Serum (30)

Tissue Extracts (2)

Tissue Homogenates (12)

Urine (4)

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Mouse PLAU / Urokinase / uPA (Sandwich ELISA) ELISA Kit - LS-F12910

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

93.75 - 6000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Rat PLAU / Urokinase / uPA (Sandwich ELISA) ELISA Kit - LS-F10464

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.025 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Media, Plasma, Serum, Tissue Extracts, Urine

Price:

1 Plate/$850

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Mouse PLAU / Urokinase / uPA (Sandwich ELISA) ELISA Kit - LS-F37177

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.625 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human PLAU / Urokinase / uPA (Sandwich ELISA) ELISA Kit - LS-F480

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

13.11 - 3200 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$760

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Mouse PLAU / Urokinase / uPA (Functional ELISA) ELISA Kit - LS-F10471

Type:

Functional

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.025 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$850

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Pig PLAU / Urokinase / uPA (Sandwich ELISA) ELISA Kit - LS-F6036

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Pig

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$779

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Pig PLAU / Urokinase / uPA (Sandwich ELISA) ELISA Kit - LS-F13848

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Pig

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human PLAU / Urokinase / uPA (Sandwich ELISA) ELISA Kit - LS-F2564

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$699

Select

Human PLAU / Urokinase / uPA (Functional ELISA) ELISA Kit - LS-F10468

Type:

Functional

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.1 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Urine

Price:

1 Plate/$850

Select

Rat PLAU / Urokinase / uPA (Functional ELISA) ELISA Kit - LS-F10478

Type:

Functional

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.02 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$850

Select

Human PLAU / Urokinase / uPA (Sandwich ELISA) ELISA Kit - LS-F10435

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.1 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Media, Plasma, Serum, Tissue Extracts, Urine

Price:

1 Plate/$850

Select

Mouse PLAU / Urokinase / uPA (Sandwich ELISA) ELISA Kit - LS-F10453

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.01 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$850

Select

Human PLAU / Urokinase / uPA (Sandwich ELISA) ELISA Kit - LS-F9993

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates, Urine

Price:

1 Plate/$744

Select

Human PLAU / Urokinase / uPA (Sandwich ELISA) ELISA Kit - LS-F5198

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.63 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Tissue Homogenates

Price:

1 Plate/$634

Select

Rat PLAU / Urokinase / uPA (Sandwich ELISA) ELISA Kit - LS-F5490

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

15.63 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$715

Select

Mouse PLAU / Urokinase / uPA (Sandwich ELISA) ELISA Kit - LS-F5491

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$782

Select

Bovine PLAU / Urokinase / uPA (Sandwich ELISA) ELISA Kit - LS-F6035

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Bovine

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$779

Select

Human PLAU / Urokinase / uPA (Sandwich ELISA) ELISA Kit - LS-F12909

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$585

Select

Chicken PLAU / Urokinase / uPA (Custom ELISA) ELISA Kit - LS-F13849

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Chicken

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Rat PLAU / Urokinase / uPA (Custom ELISA) ELISA Kit - LS-F13846

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Bovine PLAU / Urokinase / uPA (Custom ELISA) ELISA Kit - LS-F13847

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Human PLAU / Urokinase / uPA (CLIA) ELISA Kit - LS-F30095

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

15.625 - 1000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Rat PLAU / Urokinase / uPA (CLIA) ELISA Kit - LS-F40607

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Rat

Range:

7.813 - 500 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Rat PLAU / Urokinase / uPA (CLIA) ELISA Kit - LS-F40614

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Rat

Range:

7.813 - 500 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Rabbit PLAU / Urokinase / uPA (Sandwich ELISA) ELISA Kit - LS-F37178

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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