Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
PLAU / Urokinase / uPA
plasminogen activator, urokinase
PLAU / Urokinase / uPA is a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | plasminogen activator, urokinase |
| Family/Subfamily: | Protease , Serine S1 |
| Synonyms: | PLAU, BDPLT5, U-PA, U-plasminogen activator, URK, Urokinase, Plasminogen activator, urinary, QPD, UPA |
| Target Sequences: | NM_002658 NP_002649.1 P00749 |
Publications (1)
1
Preclinical evaluation of [111 In]MICA-401, an activity-based probe for SPECT imaging of in vivo uPA activity. Christel Vangestel, David Thomae, Jeroen Van Soom, Johan Ides, Leonie Wyffels, Patrick Pauwels, Sigrid Stroobants, Pieter Van der Veken, Viktor Magdolen, Jurgen Joossens, Koen Augustyns, Steven Staelens. Contrast media & molecular imaging. 2016 November;11:448-458. [Full Text Article]
[PubMed:27558262]
Related Antibodies: LS-C150831.
☰ Filters
Products
Antibodies
(122)
Type
Primary
(122)
Target
PLAU / Urokinase / uPA
(122)
Reactivity
Human
(76)
Mouse
(23)
Rat
(23)
Chimpanzee
(3)
Dog
(5)
Gibbon
(3)
Monkey
(1)
Orangutan
(3)
Pig
(8)
Rabbit
(5)
Application
IHC
(26)
IHC-Fr
(6)
IHC-P
(9)
WB
(99)
Flo
(4)
ELISA
(75)
IF
(5)
IP
(1)
Peptide-ELISA
(2)
RIA
(2)
Host
rabbit
(71)
mouse
(29)
goat
(2)
sheep
(20)
Product Group
IHCPlus
(1)
Isotype
IgG
(61)
IgG1
(16)
IgG1,k
(1)
IgG2a
(5)
Clonality
monoclonal mc
(29)
polyclonal pc
(93)
Clone
05
(2)
10D7.2
(1)
1A2G4G11
(1)
2G6.2
(1)
3B8
(1)
724-3A1-8
(2)
724-3G6-5
(2)
OTI1D4
(2)
OTI5H4
(2)
OTI6H1
(2)
OTI6H4
(2)
Format
APC
(3)
APC Conjugated
(6)
Biotin Conjugated
(15)
Carrier-free
(4)
Cy3 Conjugated
(3)
Cy7 Conjugated
(3)
FITC Conjugated
(17)
HRP Conjugated
(15)
PE Conjugated
(6)
Preservative Free
(4)
Unconjugated
(57)
Epitope
aa107-379
(8)
aa17-432
(8)
aa180-433
(8)
aa21-168
(8)
aa396-426
(7)
C-Terminus
(4)
N-Terminus
(2)
Internal
(1)
Leu239
(1)
aa190-239
(1)
aa304-331
(1)
Publications
No
(121)
Yes
(1)
PLAU / Urokinase / uPA Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
ELISA, IHC, IHC-Fr, WB
Unconjugated
100 µg/$731; 1 mg/$5,104
PLAU / Urokinase / uPA Rabbit anti-Human Polyclonal (aa396-426) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
PLAU / Urokinase / uPA Goat anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-Fr, IHC-P, RIA, WB
Unconjugated
500 µg/$688
PLAU / Urokinase / uPA Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
ELISA, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µl/$380; 1 ml/$493; 10 ml/$3,447
PLAU / Urokinase / uPA Mouse anti-Human Monoclonal (aa107-379) (OTI5H4) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
PLAU / Urokinase / uPA Rabbit anti-Rat Polyclonal Antibody
Rat
ELISA, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$866; 1 mg/$5,871
PLAU / Urokinase / uPA Mouse anti-Human Monoclonal (724-3A1-8) Antibody
Human
ELISA, WB
Unconjugated
1 mg/$635; 10 mg/$4,676
PLAU / Urokinase / uPA Rabbit anti-Mouse Polyclonal (aa180-433) Antibody
Mouse
IHC, IHC-P, WB
Unconjugated
50 µl/$460
PLAU / Urokinase / uPA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$331
PLAU / Urokinase / uPA Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-Fr, IHC-P, RIA, WB
Unconjugated
500 µg/$649
PLAU / Urokinase / uPA Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
1 mg/$990
PLAU / Urokinase / uPA Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
1 mg/$990
PLAU / Urokinase / uPA Mouse anti-Human Monoclonal (N-Terminus) (10D7.2) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$919
PLAU / Urokinase / uPA Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
PLAU / Urokinase / uPA Sheep anti-Mouse Polyclonal Antibody
Mouse, Rat
ELISA, WB
Unconjugated
100 µg/$383; 1 mg/$498; 10 mg/$2,252
PLAU / Urokinase / uPA Sheep anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$383; 1 mg/$498; 10 mg/$2,252
PLAU / Urokinase / uPA Rabbit anti-Human Polyclonal (aa396-426) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
200 µl/$734
PLAU / Urokinase / uPA Rabbit anti-Human Polyclonal (aa396-426) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
PLAU / Urokinase / uPA Rabbit anti-Human Polyclonal (aa396-426) (APC) Antibody
Human
ELISA, Flo, IF, IHC, WB
APC Conjugated
200 µl/$952
PLAU / Urokinase / uPA Rabbit anti-Human Polyclonal (aa396-426) (PE) Antibody
Human
ELISA, Flo, IF, IHC, WB
PE Conjugated
200 µl/$952
PLAU / Urokinase / uPA Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
Unconjugated
100 µg/$380; 1 mg/$493; 10 mg/$3,447
PLAU / Urokinase / uPA Rabbit anti-Human Polyclonal Antibody
Human
Unconjugated
1 mg/$546; 10 mg/$3,573
PLAU / Urokinase / uPA Rabbit anti-Mouse Polyclonal (aa180-433) (PE) Antibody
Mouse
WB
PE Conjugated
100 µl/$392; 200 µl/$470; 500 µl/$798; 1 ml/$951; 2 ml/$1,211; 5 ml/$2,269
PLAU / Urokinase / uPA Rabbit anti-Mouse Polyclonal (aa180-433) (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$392; 200 µl/$470; 500 µl/$798; 1 ml/$951; 2 ml/$1,211; 5 ml/$2,269
PLAU / Urokinase / uPA Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Viewing 1-25
of 122
product results
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
