Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Location


Corporate Headquarters

Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States

Telephone Numbers



Customer Service: (800) 227-6666 / (650) 697-3600


Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

PLA2R / PLA2R1

phospholipase A2 receptor 1, 180kDa

Receptor for secretory phospholipase A2 (sPLA2). Acts as a receptor for phosholipase sPLA2-IB/PLA2G1B but not sPLA2-IIA/PLA2G2A. Also able to bind to snake PA2-like toxins. Although its precise function remains unclear, binding of sPLA2 to its receptor participates in both positive and negative regulation of sPLA2 functions as well as clearance of sPLA2. Binding of sPLA2-IB/PLA2G1B induces various effects depending on the cell type, such as activation of the mitogen-activated protein kinase (MAPK) cascade to induce cell proliferation, the production of lipid mediators, selective release of arachidonic acid in bone marrow-derived mast cells. In neutrophils, binding of sPLA2-IB/PLA2G1B can activate p38 MAPK to stimulate elastase release and cell adhesion. May be involved in responses in proinflammatory cytokine productions during endotoxic shock. Also has endocytic properties and rapidly internalizes sPLA2 ligands, which is particularly important for the clearance of extracellular sPLA2s to protect their potent enzymatic activities. The soluble secretory phospholipase A2 receptor form is circulating and acts as a negative regulator of sPLA2 functions by blocking the biological functions of sPLA2-IB/PLA2G1B.

Gene Name: phospholipase A2 receptor 1, 180kDa
Family/Subfamily: Phospholipase , not assigned-Phospholipase
Synonyms: PLA2R1, CLEC13C, M-type receptor, PLA2IR, PLA2-R, PLA2G1R, PLA2R
Target Sequences: NM_007366 NP_031392.3 Q13018

Publications (1)

1
A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier. Petrosyan A, Cravedi P, Villani V, Angeletti A, Manrique J, Renieri A, De Filippo RE, Perin L, Da Sacco S. Nature communications. 2019 August;10:3656. [Full Text Article] [PubMed:31409793] [PMC:PMC6692336] Related Antibodies: LS-C153547.

☰ Filters
Antibodies (27)
ELISA Kits (12)
Proteins (9)
Custom (2)
Over-Expression Lysate (2)
Primary (27)
Recombinant (7)
Sandwich (9)
Sandwich CLIA (1)
PLA2R / PLA2R1 (48)
Human (24)
Mouse (11)
Rat (2)
Chicken (1)
Monkey (2)
Porcine (1)
Rabbit (1)
Sheep (1)
IHC (2)
WB (22)
Flo (1)
ELISA (6)
Peptide-ELISA (1)
rabbit (26)
goat (1)
IgG (7)
polyclonal pc (27)
12 x 8-Well Microstrips (1)
96-Well Microplate (1)
96-Well Strip Plate (10)
APC (2)
APC Conjugated (2)
Biotin Conjugated (3)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (10)
aa1418-1487 (8)
aa385-643 (8)
aa395-530 (4)
C-Terminus (2)
aa946-957 (1)
No (47)
Yes (1)
Plasma (5)
Serum (5)
Tissue Homogenates (2)
6His, N-terminus (1)
DDK,C-terminus (1)
His (2)
His-GST-S (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (8)
Mouse (1)
293T Cells (1)
CHO Cells (1)
E. coli (3)
HEK 293 Cells (2)
Mammalian Cells (1)
Yeast (1)
Purified (1)
Select
PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$440; 100 µg/$480
PLA2R / PLA2R1 Antibody - PLA2R1 antibody (1 ug/ml) staining of Human Ileum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Select
PLA2R / PLA2R1 Goat anti-Human Polyclonal (aa946-957) Antibody
Human, Monkey
Flo, Peptide-ELISA
Unconjugated
100 µg/$503
PLA2R / PLA2R1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$730
PLA2R / PLA2R1 Protein
Select
CHO Cells
DDK,C-terminus
77.5 kDa
50 µg/$677
PLA2R / PLA2R1 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
PLA2R / PLA2R1 Antibody - Western blot of PLA2R / PLA2R1 antibody.
Select
PLA2R / PLA2R1 Rabbit anti-Mouse Polyclonal (aa1418-1487) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
PLA2R / PLA2R1 Antibody - Western blot of PLA2R / PLA2R1 antibody.
Select
PLA2R / PLA2R1 Rabbit anti-Mouse Polyclonal (aa1418-1487) (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639
PLA2R / PLA2R1 Antibody - Western blot of PLA2R / PLA2R1 antibody.
Select
PLA2R / PLA2R1 Rabbit anti-Mouse Polyclonal (aa1418-1487) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
PLA2R / PLA2R1 Antibody - Western blot of PLA2R / PLA2R1 antibody.
Select
PLA2R / PLA2R1 Rabbit anti-Mouse Polyclonal (aa1418-1487) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765
PLA2R / PLA2R1 Antibody - Western blot of PLA2R / PLA2R1 antibody.
Select
PLA2R / PLA2R1 Rabbit anti-Mouse Polyclonal (aa1418-1487) (Cy3) Antibody
Mouse
WB
Cy3 Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
PLA2R / PLA2R1 Protein - Recombinant Phospholipase A2 Receptor 1 By SDS-PAGE
Select
E. coli
His-T7
33.6 kDa
10 µg/$292; 50 µg/$512; 100 µg/$817; 200 µg/$1,018; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359
PLA2R / PLA2R1 Antibody
Select
PLA2R / PLA2R1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
PLA2R / PLA2R1 Protein
Select
Yeast
His
17.45 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
PLA2R / PLA2R1 Antibody - Western blot All Lanes: PLA2R1 antibody IgG at 0.78ug/ml+ Jurkat whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 169,153 kDa Observed band size: 169 kDa
Select
PLA2R / PLA2R1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µl/$294; 100 µl/$360
PLA2R / PLA2R1 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
PLA2R / PLA2R1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
152.81 kDa
100 µg/$710
PLA2R / PLA2R1 Antibody - Immunohistochemistry of paraffin-embedded rat liver using PLA2R1 antibodyat dilution of 1:100 (40x lens).
Select
PLA2R / PLA2R1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
PLA2R / PLA2R1 Antibody - Immunohistochemistry of paraffin-embedded Rat liver using PLA2R1 Polyclonal Antibody at dilution of 1:100 (40x lens).
Select
PLA2R / PLA2R1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
200 µl/$468
PLA2R / PLA2R1 Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue using PLA2R1 Antibody at dilution of 1:100
Select
PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (aa395-530) Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
Select
PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (aa395-530) (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (aa395-530) (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
PLA2R / PLA2R1 Antibody - Western blot of recombinant PLA2R / PLA2R1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (aa385-643) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
PLA2R / PLA2R1 Antibody - Western blot of recombinant PLA2R / PLA2R1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (aa385-643) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
PLA2R / PLA2R1 Antibody - Western blot of recombinant PLA2R / PLA2R1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (aa385-643) (PE) Antibody
Human
WB
PE Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008
Viewing 1-25 of 48 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).