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PKP1 / Plakophilin 1

plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)

PKP1 / Plakophilin 1 is a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)
Synonyms: PKP1, B6P, Band 6 protein, Plakophilin 1, Plakophilin-1, Plakophilin
Target Sequences: NM_000299 NP_000290.2 Q13835

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
PKP1 / Plakophilin 1 (5)
No (5)
GST, N-terminus (1)
His-GST (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
PKP1 / Plakophilin 1 Protein - Recombinant Plakophilin 1 By SDS-PAGE
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E. coli
His-GST
58.8 kDa
10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198
PKP1 / Plakophilin 1 Protein - Purified recombinant protein PKP1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
80.3 kDa
20 µg/$1,107
PKP1 / Plakophilin 1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PKP1 / Plakophilin 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
80.3 kDa
20 µg/$215
PKP1 / Plakophilin 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
80.3 kDa
100 µg/$710
Viewing 1-5 of 5 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).