Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
PKLR is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Name: | pyruvate kinase, liver and RBC |
Synonyms: | PKLR, PKL, Pyruvate kinase, liver and RBC, Pyruvate kinase type L, Red cell/liver pyruvate kinase, RPK, PK1, PKR, Pyruvate kinase 1, Pyruvate kinase isozymes R/L, R-type/L-type pyruvate kinase, PKRL, Pyruvate kinase isozyme R/L |
Target Sequences: | NM_000298 NP_000289.1 P30613 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.