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PK2 / PROK2

prokineticin 2

PK2 / PROK2 is a protein expressed in the suprachiasmatic nucleus (SCN) circadian clock that may function as the output component of the circadian clock. The secreted form of the encoded protein may also serve as a chemoattractant for neuronal precursor cells in the olfactory bulb. Proteins from other vertebrates which are similar to this gene product were isolated based on homology to snake venom and secretions from frog skin, and have been shown to have diverse functions. Mutations in this gene are associated with Kallmann syndrome 4. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: prokineticin 2
Synonyms: PROK2, BV8, HH4, MIT1, Prokineticin 2, Prokineticin-2, KAL4, PK2, Protein Bv8 homolog
Target Sequences: NM_021935 NP_068754.1

Publications (1)

1
Prokineticin-2 is associated with metabolic syndrome in a middle-aged and elderly Chinese population. Yong Wang, Xiaoyan Guo, Heng Ma, Lin Lu, Ruiyan Zhang. Lipids in health and disease. 2016 January;15:1. [Full Text Article] [PubMed:26728949] [PMC:PMC4700697]

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Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
PK2 / PROK2 (8)
No (8)
GST, N-terminus (1)
His (2)
His-GST (1)
Myc-DDK (Flag) (2)
Human (4)
Mouse (2)
Rat (1)
293T Cells (1)
E. coli (5)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (2)
PK2 / PROK2 Protein - Recombinant Prokineticin 2 By SDS-PAGE
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E. coli
His
10.2 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
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E. coli
None
Less than 0.1 ng/µg of protein (less than 1EU/µg).
8.8 kDa
5 µg/$268; 20 µg/$349
PK2 / PROK2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
2 µg/$439
PK2 / PROK2 Protein - Recombinant Prokineticin 2 By SDS-PAGE
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E. coli
His-GST
41.2 kDa
10 µg/$270; 50 µg/$372; 100 µg/$592; 200 µg/$742; 1 mg/$1,786; 500 µg/$1,352; 5 mg/$2,742; 2 mg/$1,966
PK2 / PROK2 Protein - Recombinant Prokineticin 2 By SDS-PAGE
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E. coli
His
13.6 kDa
10 µg/$273; 50 µg/$392; 100 µg/$625; 200 µg/$782; 1 mg/$1,847; 500 µg/$1,404; 5 mg/$2,807; 2 mg/$2,029
PK2 / PROK2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
8.8 kDa
20 µg/$150
PK2 / PROK2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
8.8 kDa
100 µg/$494
Select
E. coli
None
Less than 0.1 ng/µg of protein (less than 1EU/µg).
11.6 kDa
20 µg/$349; 5 µg/$268
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).