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Has E2-dependent E3 ubiquitin-protein ligase activity. Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation. Essential for PKA-mediated long-term memory processes.
Gene Name: | praja ring finger 2, E3 ubiquitin protein ligase |
Synonyms: | PJA2, KIAA0438, Neurodap1, Praja ring finger 2, Praja2, RING finger protein 131, RNF131 |
Target Sequences: | NM_014819 NP_055634.3 O43164 |
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