PITRM1 / MP1

pitrilysin metallopeptidase 1

ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

PITRM1 / MP1 (6)

Publications

No (6)

Tag

GST (1)

His (2)

Myc-DDK (Flag) (3)

Species

Human (4)

Rat (1)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human PITRM1 / MP1 Protein (Recombinant GST) (Full Length) - LS-G32201

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

84.48 kDa

Price:

2 µg/$439

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Human PITRM1 / MP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87467

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

117.2 kDa

Price:

20 µg/$150

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Human PITRM1 / MP1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70568

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

117.2 kDa

Price:

20 µg/$1,107

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PITRM1 / MP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G113627

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

117.2 kDa

Price:

100 µg/$494

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Human PITRM1 / MP1 Protein (Recombinant His) (aa544-806) - LS-G13854

Source:

E. coli

Tag:

His

Molecular Weight:

30.7 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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Rat PITRM1 / MP1 Protein (Recombinant His) (aa653-926) - LS-G13855

Source:

E. coli

Tag:

His

Molecular Weight:

32.4 kDa

Price:

10 µg/$289; 50 µg/$492; 100 µg/$785; 200 µg/$982; 1 mg/$2,119; 500 µg/$1,646; 5 mg/$3,431; 2 mg/$2,309

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