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Infectious Disease
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Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
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Customer Service: (800) 227-6666 / (650) 697-3600
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PIM3 / PIM-3
pim-3 oncogene
Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L), the regulation of cell cycle progression, protein synthesis and by regulation of MYC transcriptional activity. Additionally to this role on tumorigenesis, can also negatively regulate insulin secretion by inhibiting the activation of MAPK1/3 (ERK1/2), through SOCS6. Involved also in the control of energy metabolism and regulation of AMPK activity in modulating MYC and PPARGC1A protein levels and cell growth.
| Gene Name: | pim-3 oncogene |
| Family/Subfamily: | Protein Kinase , PIM |
| Synonyms: | PIM3, KID1, Pim-3 oncogene, Serine/threonine kinase Pim-3, Pim-3 |
| Target Sequences: | SK200D SK200P Q86V86 |
☰ Filters
Products
Antibodies
(19)
ELISA Kits
(6)
Proteins
(5)
Type
Custom
(2)
Over-Expression Lysate
(2)
Primary
(19)
Recombinant
(3)
Sandwich
(3)
Sandwich CLIA
(1)
Target
PIM3 / PIM-3
(30)
Reactivity
Human
(23)
Mouse
(3)
Rat
(1)
Application
IHC
(8)
IHC-P
(1)
WB
(16)
ELISA
(10)
IF
(1)
Host
rabbit
(19)
Product Group
IHCPlus
(1)
Isotype
IgG
(10)
Clonality
polyclonal pc
(19)
Format
96-Well Strip Plate
(6)
APC
(1)
APC Conjugated
(2)
Azide-free
(1)
Biotin Conjugated
(3)
Cy3 Conjugated
(1)
Cy7 Conjugated
(1)
FITC Conjugated
(3)
HRP Conjugated
(3)
PE Conjugated
(2)
Unconjugated
(4)
Epitope
aa1-326
(8)
aa259-288
(7)
Publications
No
(30)
Sample Type
Plasma
(4)
Serum
(4)
Tissue Homogenates
(3)
Tag
GST, N-terminus
(1)
His-T7
(1)
Myc-DDK (Flag)
(3)
Species
Human
(4)
Source
293T Cells
(1)
E. coli
(1)
HEK 293 Cells
(2)
Wheat Germ Extract
(1)
PIM3 / PIM-3 Rabbit anti-Human Polyclonal (aa259-288) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
PIM3 / PIM-3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
PIM3 / PIM-3 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
PIM3 / PIM-3 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
PIM3 / PIM-3 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
PIM3 / PIM-3 Rabbit anti-Human Polyclonal (aa259-288) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
PIM3 / PIM-3 Rabbit anti-Human Polyclonal (aa259-288) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
PIM3 / PIM-3 Rabbit anti-Human Polyclonal (aa259-288) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
PIM3 / PIM-3 Rabbit anti-Human Polyclonal (aa259-288) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
PIM3 / PIM-3 Rabbit anti-Human Polyclonal (aa259-288) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
PIM3 / PIM-3 Rabbit anti-Human Polyclonal (aa259-288) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
PIM3 / PIM-3 Rabbit anti-Human Polyclonal (aa1-326) Antibody
Human
WB
Unconjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$597; 2 ml/$826; 5 ml/$1,352
PIM3 / PIM-3 Rabbit anti-Human Polyclonal (aa1-326) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$351; 200 µl/$411; 500 µl/$618; 1 ml/$774; 2 ml/$1,010; 5 ml/$1,757
PIM3 / PIM-3 Rabbit anti-Human Polyclonal (aa1-326) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$329; 200 µl/$381; 500 µl/$550; 1 ml/$654; 2 ml/$890; 5 ml/$1,487
PIM3 / PIM-3 Rabbit anti-Human Polyclonal (aa1-326) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$362; 200 µl/$427; 500 µl/$666; 1 ml/$826; 2 ml/$1,067; 5 ml/$1,892
PIM3 / PIM-3 Rabbit anti-Human Polyclonal (aa1-326) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$427; 200 µl/$519; 500 µl/$916; 1 ml/$1,084; 2 ml/$1,441; 5 ml/$2,703
PIM3 / PIM-3 Rabbit anti-Human Polyclonal (aa1-326) (PE) Antibody
Human
WB
PE Conjugated
100 µl/$427; 200 µl/$519; 500 µl/$916; 1 ml/$1,084; 2 ml/$1,441; 5 ml/$2,703
PIM3 / PIM-3 Rabbit anti-Human Polyclonal (aa1-326) (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$535; 200 µl/$714; 500 µl/$1,236; 1 ml/$1,545; 2 ml/$2,163; 5 ml/$4,053
PIM3 / PIM-3 Rabbit anti-Human Polyclonal (aa1-326) (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$427; 200 µl/$519; 500 µl/$916; 1 ml/$1,084; 2 ml/$1,441; 5 ml/$2,703
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HEK 293 Cells
Myc-DDK (Flag)
35.7 kDa
20 µg/$1,107
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$792
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
Viewing 1-25
of 30
product results
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