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PIK3C3 / VPS34
phosphatidylinositol 3-kinase, catalytic subunit type 3
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.
| Gene Name: | phosphatidylinositol 3-kinase, catalytic subunit type 3 |
| Family/Subfamily: | Non-Protein Kinase , not assigned-Non-Protein Kinase |
| Synonyms: | PIK3C3, HVps34, Phosphatidylinositol 3-kinase, VPS34, PI3-kinase type 3, PI3K type 3, PtdIns-3-kinase type 3 |
| Target Sequences: | NM_002647 NP_002638.2 Q8NEB9 |
Publications (1)
1
Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells. Scarlatti F, Maffei R, Beau I, Codogno P, Ghidoni R. Cell death and differentiation. 2008 15:1318-29.
[PubMed:18421301]
Related Antibodies: LS-C163703.
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Products
Proteins
(5)
Type
Over-Expression Lysate
(2)
Recombinant
(3)
Target
PIK3C3 / VPS34
(5)
Publications
No
(5)
Tag
GST
(1)
His, N-Terminal
(1)
Myc-DDK (Flag)
(3)
Species
Human
(4)
Source
293T Cells
(1)
E. coli
(1)
HEK 293 Cells
(2)
Wheat Germ Extract
(1)
Purification
Purified
(1)
E. coli
His, N-Terminal
32.9 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
Wheat Germ Extract
GST
127.9 kDa
10 µg/$479; 25 µg/$670
HEK 293 Cells
Myc-DDK (Flag)
101.4 kDa
20 µg/$1,107
293T Cells
Myc-DDK (Flag)
101.4 kDa
20 µg/$150
HEK 293 Cells
Myc-DDK (Flag)
101.4 kDa
100 µg/$494
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