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PIK3C3 / VPS34
phosphatidylinositol 3-kinase, catalytic subunit type 3
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.
| Gene Name: | phosphatidylinositol 3-kinase, catalytic subunit type 3 |
| Family/Subfamily: | Non-Protein Kinase , not assigned-Non-Protein Kinase |
| Synonyms: | PIK3C3, HVps34, Phosphatidylinositol 3-kinase, VPS34, PI3-kinase type 3, PI3K type 3, PtdIns-3-kinase type 3 |
| Target Sequences: | NM_002647 NP_002638.2 Q8NEB9 |
Publications (1)
1
Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells. Scarlatti F, Maffei R, Beau I, Codogno P, Ghidoni R. Cell death and differentiation. 2008 15:1318-29.
[PubMed:18421301]
Related Antibodies: LS-C163703.
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Products
ELISA Kits
(3)
Type
Sandwich
(2)
Sandwich CLIA
(1)
Target
PIK3C3 / VPS34
(3)
Reactivity
Human
(1)
Mouse
(1)
Rat
(1)
Format
96-Well Strip Plate
(3)
Publications
No
(3)
Sample Type
Cell Lysates
(2)
Cell Supernatant
(1)
Plasma
(1)
Serum
(1)
Tissue Homogenates
(2)
Sandwich
96-Well Strip Plate
Mouse
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$748
Sandwich CLIA
96-Well Strip Plate
Rat
15.625 - 1000 pg/ml
Chemiluminescent
Cell Supernatant, Plasma, Serum
1 Plate/$669
Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
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