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PIGV

phosphatidylinositol glycan anchor biosynthesis, class V

PIGV is a mannosyltransferase enzyme involved in the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is a complex glycolipid that functions as a membrane anchor for many proteins and plays a role in multiple cellular processes including protein sorting and signal transduction. The encoded protein is localized to the endoplasmic reticulum and transfers the second mannose to the GPI backbone. Mutations in this gene are associated with hyperphosphatasia mental retardation syndrome. Alternatively spliced transcript variants have been observed for this gene.

Gene Name: phosphatidylinositol glycan anchor biosynthesis, class V
Synonyms: PIGV, GPI mannosyltransferase II, GPI-MT-II, HPMRS1, GPI mannosyltransferase 2, Ybr004c homolog, PIG-V
Target Sequences: NM_017837 NP_060307.2 Q9NUD9

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
PIGV (3)
No (3)
GST (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
PIGV Protein - 12.5% SDS-PAGE of human PIGV stained with Coomassie Blue
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Wheat Germ Extract
GST
82.1 kDa
2 µg/$439
PIGV Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
55.5 kDa
20 µg/$150
PIGV Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
55.5 kDa
100 µg/$494
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).