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PI4K2B

phosphatidylinositol 4-kinase type 2 beta

Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Contributes to the production of InsP3 in stimulated cells and is likely to be involved in the regulation of vesicular trafficking.

Gene Name: phosphatidylinositol 4-kinase type 2 beta
Family/Subfamily: Non-Protein Kinase
Synonyms: PI4K2B, PI4KIIB, PIK42B, PI4KII-BETA
Target Sequences: NM_018323 NP_060793.2 Q8TCG2

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Proteins (3)
Over-Expression Lysate (2)
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PI4K2B (3)
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Myc-DDK (Flag) (3)
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293T Cells (1)
HEK 293 Cells (2)
PI4K2B Protein - Purified recombinant protein PI4K2B was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
54.6 kDa
20 µg/$1,107
PI4K2B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
54.6 kDa
100 µg/$494
PI4K2B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
54.6 kDa
20 µg/$150
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).