PHF2

PHD finger protein 2

Lysine demethylase that demethylates both histones and non-histone proteins. Enzymatically inactive by itself, and becomes active following phosphorylation by PKA: forms a complex with ARID5B and mediates demethylation of methylated ARID5B. Demethylation of ARID5B leads to target the PHF2-ARID5B complex to target promoters, where PHF2 mediates demethylation of dimethylated 'Lys-9' of histone H3 (H3K9me2), followed by transcription activation of target genes. The PHF2-ARID5B complex acts as a coactivator of HNF4A in liver. PHF2 is recruited to trimethylated 'Lys-4' of histone H3 (H3K4me3) at rDNA promoters and promotes expression of rDNA.

☰ Filters

Products

Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

PHF2 (3)

Publications

No (3)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Select

Human PHF2 Protein (Recombinant GST, N-terminus) (aa2-100) - LS-G59587

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Select

Human PHF2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84244

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

120.6 kDa

Price:

20 µg/$215

Select

PHF2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115993

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

120.6 kDa

Price:

100 µg/$710

Viewing 1-3 of 3 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.