PHACTR4

Phosphatase And Actin Regulator 4

Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1 by interacting with PPP1CA and preventing phosphorylation of PPP1CA at 'Thr-320'. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to dephosphorylation and subsequent activation of cofilin (COF1 or COF2) and repression of the integrin signaling through the RHO/ROCK pathway.

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Products

Antibodies (15)

Proteins (5)

Type

Over-Expression Lysate (4)

Primary (15)

Recombinant (1)

Target

PHACTR4 (20)

Reactivity

Human (15)

Mouse (7)

Rat (1)

Application

IHC (2)

IHC-P (1)

WB (14)

ELISA (11)

ICC (1)

IF (1)

Peptide-ELISA (2)

Host

rabbit (15)

Isotype

IgG (12)

Clonality

polyclonal pc (15)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

PE Conjugated (1)

Unconjugated (10)

Epitope

aa536-565 (7)

aa139-378 (2)

340-420 aa, Internal (1)

aa346-395 (1)

Publications

No (20)

Tag

GST (1)

Myc-DDK (Flag) (4)

Species

Human (3)

Source

293T Cells (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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PHACTR4 Antibody LS-C667632

Antibody:

PHACTR4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$331

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PHACTR4 Antibody (340-420 aa, Internal) LS-C385459

Antibody:

PHACTR4 Rabbit anti-Human Polyclonal (340-420 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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PHACTR4 Antibody (aa139-378) LS-C178615

Antibody:

PHACTR4 Rabbit anti-Human Polyclonal (aa139-378) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$332

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PHACTR4 Antibody (aa139-378) LS-C178889

Antibody:

PHACTR4 Rabbit anti-Human Polyclonal (aa139-378) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µl/$332

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PHACTR4 Antibody LS-C742693

Antibody:

PHACTR4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

PHACTR4 Antibody (aa536-565) LS-C323978

Antibody:

PHACTR4 Rabbit anti-Human Polyclonal (aa536-565) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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PHACTR4 Antibody (aa536-565, Biotin) LS-C216733

Antibody:

PHACTR4 Rabbit anti-Human Polyclonal (aa536-565) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

PHACTR4 Antibody (aa536-565, FITC) LS-C216734

Antibody:

PHACTR4 Rabbit anti-Human Polyclonal (aa536-565) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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PHACTR4 Antibody (aa536-565, APC) LS-C216732

Antibody:

PHACTR4 Rabbit anti-Human Polyclonal (aa536-565) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

PHACTR4 Antibody (aa536-565, Azide-free, HRP) LS-C216735

Antibody:

PHACTR4 Rabbit anti-Human Polyclonal (aa536-565) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

PHACTR4 Antibody (aa536-565, PE) LS-C216736

Antibody:

PHACTR4 Rabbit anti-Human Polyclonal (aa536-565) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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PHACTR4 Antibody (aa346-395) LS-C200484

Antibody:

PHACTR4 Rabbit anti-Human Polyclonal (aa346-395) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

PHACTR4 Antibody LS-C809394

Antibody:

PHACTR4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

PHACTR4 Antibody (aa536-565) LS-C163559

Antibody:

PHACTR4 Rabbit anti-Human Polyclonal (aa536-565) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

PHACTR4 Antibody LS-C816962

Antibody:

PHACTR4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC-P

Format:

Unconjugated

Price:

100 µl/$412

Select

Human PHACTR4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88572

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

78 kDa

Price:

20 µg/$150

Select

Human PHACTR4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88574

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

78.9 kDa

Price:

20 µg/$150

Select

PHACTR4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110138

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

78.9 kDa

Price:

100 µg/$494

Select

Human PHACTR4 Protein (Recombinant GST) (Full Length) - LS-G35099

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

95.6 kDa

Price:

2 µg/$439

Select

PHACTR4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119386

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

78 kDa

Price:

100 µg/$494

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