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Binds actin monomers (G actin) and plays a role in the reorganization of the actin cytoskeleton and in formation of actin stress fibers. Plays a role in cell motility. Plays a role in the formation of tubules by endothelial cells. Regulates PPP1CA activity. Required for normal cell survival.
Gene Name: | phosphatase and actin regulator 1 |
Synonyms: | PHACTR1, DJ257A7.2, RPEL1, RPEL, RPEL repeat containing 1, KIAA1733 |
Target Sequences: | NM_030948 NP_112210.1 Q9C0D0 |
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