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Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.
Gene Name: | peptidoglycan recognition protein 3 |
Synonyms: | PGLYRP3, PGLYRPIalpha, PGRPIA, PGRP-Ialpha, PGRP-I-alpha |
Target Sequences: | NM_052891 NP_443123.1 Q96LB9 |
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