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PGGT1B
protein geranylgeranyltransferase type I, beta subunit
Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.
| Gene Name: | protein geranylgeranyltransferase type I, beta subunit |
| Synonyms: | PGGT1B, BGGI, GGTI, GGTase-I-beta |
| Target Sequences: | NM_005023 NP_005014.2 P53609 |
![PGGT1B Antibody - Immunoperoxidase of monoclonal antibody to PGGT1B on formalin-fixed paraffin-embedded human kidney. [antibody concentration 1.2 ug/ml]](https://lsbio-7d62.kxcdn.com/image2/pggt1b-antibody-clone-5e4-ls-c133375/51427_5188910.jpg)
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