PGC / Pepsin C

progastricsin (pepsinogen C)

PGC / Pepsin C is an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.

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Products

Proteins (15)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (5)

Recombinant (9)

Target

PGC / Pepsin C (15)

Publications

No (15)

Tag

6His, N-terminus (3)

8His, N-terminus (1)

GST (1)

His (4)

His-GST (1)

Myc-DDK (Flag) (5)

Species

Human (10)

Mouse (1)

Rat (2)

Source

293T Cells (2)

E. coli (5)

HEK 293 Cells (5)

Human Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (2)

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Human PGC / Pepsin C Protein (Recombinant 8His, N-terminus) (aa61-388) - LS-G11714

Source:

E. coli

Tag:

8His, N-terminus

Molecular Weight:

36.9 kDa

Price:

10 µg/$255; 50 µg/$323; 100 µg/$450; 200 µg/$562; 1 mg/$1,480; 500 µg/$1,096; 5 mg/$2,395; 2 mg/$1,646

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Human PGC / Pepsin C Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66661

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.5 kDa

Price:

20 µg/$1,107

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Rat PGC / Pepsin C Protein (Recombinant His) (aa17-392) - LS-G11717

Source:

E. coli

Tag:

His

Molecular Weight:

42.5 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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Mouse PGC / Pepsin C Protein (Recombinant His-GST) (aa17-392) - LS-G23944

Source:

E. coli

Tag:

His-GST

Molecular Weight:

71.0 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human PGC / Pepsin C Protein (Recombinant GST) (Full Length) - LS-G29712

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

68.8 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PGC / Pepsin C Protein (Over-Expression Cell Culture Supernatant 6His, N-terminus) (Ala17-Ala388) - LS-G26926

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

41 kDa

Price:

200 µl/$283

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Human PGC / Pepsin C Protein (Over-Expression Lysate 6His, N-terminus) (Ala17-Ala388) - LS-G26790

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

41 kDa

Price:

100 µg/$298

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PGC / Pepsin C Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G129609

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.7 kDa

Price:

100 µg/$494

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Human PGC / Pepsin C Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78235

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.7 kDa

Price:

20 µg/$150

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Human PGC / Pepsin C Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78236

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.43 kDa

Price:

20 µg/$150

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PGC / Pepsin C Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117856

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.43 kDa

Price:

100 µg/$494

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Human PGC / Pepsin C Protein (Recombinant His) (Ile153-Ile239) - LS-G97769

Source:

E. coli

Tag:

His

Molecular Weight:

10.9 kDa

Price:

50 µg/$721

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Rat PGC / Pepsin C Protein (Recombinant His) (Met1-Val392) - LS-G98456

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

42.5 kDa

Price:

20 µg/$649

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Human PGC / Pepsin C Protein (Recombinant His) (Met1-Ala388) - LS-G98637

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

42 kDa

Price:

20 µg/$603

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Human PGC / Pepsin C Protein (Recombinant 6His, N-terminus) (Ala17-Ala388) - LS-G26421

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

41 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365

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