PGAP3 / PERLD1

post-GPI attachment to proteins 3

PGAP3 / PERLD1 is a glycosylphosphatidylinositol (GPI)-specific phospholipase that primarily localizes to the Golgi apparatus. This ubiquitously expressed gene is predicted to encode a seven-transmembrane protein that removes unsaturated fatty acids from the sn-2 position of GPI. The remodeling of the constituent fatty acids on GPI is thought to be important for the proper association between GPI-anchored proteins and lipid rafts. The tethering of proteins to plasma membranes via posttranslational GPI-anchoring is thought to play a role in protein sorting and trafficking. Mutations in this gene cause the autosomal recessive neurologic disorder hyperphosphatasia with mental retardation syndrome 4 (HPMRS4). Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

PGAP3 / PERLD1 (3)

Publications

No (3)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human PGAP3 / PERLD1 Protein (Recombinant GST) (Full Length) - LS-G36090

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

62.9 kDa

Price:

2 µg/$439

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Human PGAP3 / PERLD1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93382

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.3 kDa

Price:

20 µg/$150

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PGAP3 / PERLD1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G108241

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.3 kDa

Price:

100 µg/$494

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