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PFDN6 / HKE2

prefoldin subunit 6

Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

Gene Name: prefoldin subunit 6
Synonyms: PFDN6, KE-2, KE2 protein, HKE2, Prefoldin subunit 6, Prefoldin 6, PFD6, H2-KE2, Protein Ke2
Target Sequences: NM_014260 NP_055075.1 O15212

Publications (1)

1
Prefoldin subunits are protected from ubiquitin-proteasome system-mediated degradation by forming complex with other constituent subunits. Miyazawa M, Tashiro E, Kitaura H, Maita H, Suto H, Iguchi-Ariga SM, Ariga H. The Journal of biological chemistry. 2011 286:19191-203. [PubMed:21478150] [PMC:PMC3103298] Related Antibodies: LS-C97157.

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
PFDN6 / HKE2 (5)
No (5)
GST (1)
His (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
PFDN6 / HKE2 Protein
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E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
PFDN6 / HKE2 Protein - 12.5% SDS-PAGE of human HKE2 stained with Coomassie Blue
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Wheat Germ Extract
GST
39.93 kDa
2 µg/$439
PFDN6 / HKE2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
14.4 kDa
20 µg/$150
PFDN6 / HKE2 Protein - Purified recombinant protein PFDN6 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
14.4 kDa
20 µg/$1,107
PFDN6 / HKE2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
14.4 kDa
100 µg/$494
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).