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PER2

period circadian clock 2

PER2 /Period circadian clock 2 is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders.

Gene Name: period circadian clock 2
Synonyms: PER2, HPER2, Period homolog 2 (Drosophila), Period 2, KIAA0347, Period (Drosophila) homolog 2, Period circadian clock 2, Period circadian protein 2, FASPS
Target Sequences: NM_022817 NP_073728.1 O15055

Publications (3)

1
Expression of clock proteins in developing tooth. Zheng L, Papagerakis S, Schnell SD, Hoogerwerf WA, Papagerakis P. Gene expression patterns : GEP. 11:202-6. (IHC; Mouse) [Full Text Article] [PubMed:21156215] [PMC:PMC3073654]
2
Calcium Sets the Clock in Ameloblasts. Raed Said, Liubov Lobanova, Silvana Papagerakis, Petros Papagerakis. Frontiers in physiology. 2020 August;11:920. [Full Text Article] [PubMed:32848861] [PMC:PMC7411184] Related Antibodies: LS-C2836.
3
Circadian rhythms regulate amelogenesis. Zheng L, Seon YJ, Mour[Character e3]o MA, Schnell S, Kim D, Harada H, Papagerakis S, Papagerakis P. Bone. 2014 Jul;55:158-65. [Full Text Article] [PubMed:23486183] [PMC:PMC3650122] Related Antibodies: LS-C2836.

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PER2 ELISA Kit
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0.313 - 20 ng/ml
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PER2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).