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Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm (By similarity). Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface.
Gene Name: | phosphoprotein enriched in astrocytes 15 |
Synonyms: | PEA15, MAT1, HMAT1, PEA-15, HUMMAT1H, MAT1H, PED |
Target Sequences: | NM_003768 NP_003759.1 Q15121 |
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