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PDYN / ProDynorphin

prodynorphin

PDYN / ProDynorphin is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene Name: prodynorphin
Family/Subfamily: Endogenous opioids , not assigned-Endogenous opioids
Synonyms: PDYN, ADCA, Beta-neoendorphin-dynorphin, Leumorphin, Preprodynorphin, Spinocerebellar ataxia 23, PENKB, Prodynorphin, Rimorphin, SCA23, Leu-enkephalin, Preproenkephalin B, Proenkephalin-B
Target Sequences: NM_024411 NP_077722.1 P01213

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Products
Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
PDYN / ProDynorphin (6)
No (6)
GST (1)
GST, N-terminus (2)
His,C-terminus (1)
Myc-DDK (Flag) (2)
Human (5)
293T Cells (1)
HEK 293 Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (3)
Purified (1)
Low endotoxin level (1)
PDYN / ProDynorphin Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
27.3 kDa
10 µg/$317; 50 µg/$524
PDYN / ProDynorphin Protein - 12.5% SDS-PAGE of human PDYN stained with Coomassie Blue
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Wheat Germ Extract
GST
54.8 kDa
2 µg/$439
PDYN / ProDynorphin Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PDYN / ProDynorphin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
26.2 kDa
100 µg/$494
PDYN / ProDynorphin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
26.2 kDa
20 µg/$150
Viewing 1-6 of 6 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).