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PDYN / ProDynorphin
prodynorphin
PDYN / ProDynorphin is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
| Gene Name: | prodynorphin |
| Family/Subfamily: | Endogenous opioids , not assigned-Endogenous opioids |
| Synonyms: | PDYN, ADCA, Beta-neoendorphin-dynorphin, Leumorphin, Preprodynorphin, Spinocerebellar ataxia 23, PENKB, Prodynorphin, Rimorphin, SCA23, Leu-enkephalin, Preproenkephalin B, Proenkephalin-B |
| Target Sequences: | NM_024411 NP_077722.1 P01213 |
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